Oneonta feels like a lively small college city—home to SUNY Oneonta (and nearby Hartwick)—with a compact downtown of restaurants, galleries, live music and easy access to parks and trails, so multi-week stays are more social and active than isolated.
If you want bigger-city options within a daytrip, Binghamton (~1 hour) and Utica (~1–1.25 hours) are the nearest regional centers for larger hospitals, shopping and evening options, giving you a small-town base plus occasional city amenities.